Plasma D-Dimer as a Marker of Urinary Tract Infection in Children

Background: Urinary tract infections (UTIs) are very common in children. Several biomarkers have been used for the diagnosis of UTI and prediction renal parenchymal involvement. Objectives: This study aimed to evaluate plasma D-dimer as a diagnostic marker Methods: cross-sectional included 41 children aged 1 month 14 years with their first febrile confirmed by positive urine culture referred Bandar Abbas Children’s Hospital, Iran, from October 1, 2017, April 2018. Participants’ demographic features, including age gender were recorded. White blood cell (WBC) count, percentage neutrophils, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), serum measured random samples all patients. Results: Out (mean age: 5.50 ± 4.01 years) evaluated this study, 6 (14.6%) male, 35 (85.4%) female. The mean level was 1496.49 2787.55 µg/L. A significant correlation found between ESR (r = 0.647, P 0.026) CRP 0.525, 0.001). Plasma not associated age; however, inversely correlated WBC count -0.327, 0.037). No relationship D-dimer, ESR, CRP, neutrophil (P > 0.05). Conclusions: According our results, culture-confirmed UTI, is positively CRP. Nevertheless, appears be influenced or gender. Further studies required confirm utility